You can reach the Port Vesyegonsk Hotel by any type of transport:
Helicopter flight from Moscow Heliport to the hotel takes about 4 hours.
Multipurpose wharf takes in all kinds of lifeboats, yachts and cruise motor boats from Moscow, Saint-Petersburg, Tver and river cities and towns of Tver and Yaroslavl regions.
To get to the hotel you should following from the Rybinsk Reservoir (Rybinskoe vodokhranilische) by 64-th navigable channel, then along the Mologa river, and following by directing marks to 121-st buoy beam.
58°39’437”N 37°16’130”E